Conduct of Clinical Trials in the Era of COVID-19: JACC Scientific Expert Panel.
Identifieur interne : 000191 ( Main/Exploration ); précédent : 000190; suivant : 000192Conduct of Clinical Trials in the Era of COVID-19: JACC Scientific Expert Panel.
Auteurs : Mitchell A. Psotka [États-Unis] ; William T. Abraham [États-Unis] ; Mona Fiuzat [États-Unis] ; Gerasimos Filippatos [Chypre (pays)] ; Joann Lindenfeld [États-Unis] ; Tariq Ahmad [États-Unis] ; Ankeet S. Bhatt [États-Unis] ; Peter E. Carson [États-Unis] ; John G F. Cleland [Royaume-Uni] ; G Michael Felker [États-Unis] ; James L. Januzzi [États-Unis] ; Dalane W. Kitzman [États-Unis] ; Eric S. Leifer [États-Unis] ; Eldrin F. Lewis [États-Unis] ; John J V. Mcmurray [Royaume-Uni] ; Robert J. Mentz [États-Unis] ; Scott D. Solomon [États-Unis] ; Norman Stockbridge [États-Unis] ; John R. Teerlink [États-Unis] ; Muthiah Vaduganathan [États-Unis] ; Orly Vardeny [États-Unis] ; David J. Whellan [États-Unis] ; Janet Wittes [États-Unis] ; Stefan D. Anker [Allemagne] ; Christopher M. O'Connor [États-Unis]Source :
- Journal of the American College of Cardiology [ 1558-3597 ] ; 2020.
Descripteurs français
- KwdFr :
- MESH :
English descriptors
- KwdEn :
- MESH :
Abstract
The coronavirus disease-2019 (COVID-19) pandemic has profoundly changed clinical care and research, including the conduct of clinical trials, and the clinical research ecosystem will need to adapt to this transformed environment. The Heart Failure Academic Research Consortium is a partnership between the Heart Failure Collaboratory and the Academic Research Consortium, composed of academic investigators from the United States and Europe, patients, the U.S. Food and Drug Administration, the National Institutes of Health, and industry members. A series of meetings were convened to address the challenges caused by the COVID-19 pandemic, review options for maintaining or altering best practices, and establish key recommendations for the conduct and analysis of clinical trials for cardiovascular disease and heart failure. This paper summarizes the discussions and expert consensus recommendations.
DOI: 10.1016/j.jacc.2020.09.544
PubMed: 33183511
Affiliations:
- Allemagne, Chypre (pays), Royaume-Uni, États-Unis
- Berlin, Californie, Caroline du Nord, Connecticut, District de Columbia, Maryland, Massachusetts, Minnesota, Ohio, Pennsylvanie, Tennessee, Virginie, Écosse
- Berlin, Glasgow
- Université de Glasgow
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Conduct of Clinical Trials in the Era of COVID-19: JACC Scientific Expert Panel.</title><author><name sortKey="Psotka, Mitchell A" sort="Psotka, Mitchell A" uniqKey="Psotka M" first="Mitchell A" last="Psotka">Mitchell A. Psotka</name><affiliation wicri:level="2"><nlm:affiliation>Inova Heart and Vascular Institute, Falls Church, Virginia. Electronic address: https://twitter.com/mpsotka.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Virginie</region></placeName><wicri:cityArea>Inova Heart and Vascular Institute, Falls Church</wicri:cityArea></affiliation></author><author><name sortKey="Abraham, William T" sort="Abraham, William T" uniqKey="Abraham W" first="William T" last="Abraham">William T. Abraham</name><affiliation wicri:level="2"><nlm:affiliation>Division of Cardiovascular Medicine, The Ohio State University, Columbus, Ohio. Electronic address: William.Abraham@osumc.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Ohio</region></placeName><wicri:cityArea>Division of Cardiovascular Medicine, The Ohio State University, Columbus</wicri:cityArea></affiliation></author><author><name sortKey="Fiuzat, Mona" sort="Fiuzat, Mona" uniqKey="Fiuzat M" first="Mona" last="Fiuzat">Mona Fiuzat</name><affiliation wicri:level="2"><nlm:affiliation>Duke University Medical Center and Duke Clinical Research Institute, Durham, North Carolina. Electronic address: https://twitter.com/mfiuzat.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Caroline du Nord</region></placeName><wicri:cityArea>Duke University Medical Center and Duke Clinical Research Institute, Durham</wicri:cityArea></affiliation></author><author><name sortKey="Filippatos, Gerasimos" sort="Filippatos, Gerasimos" uniqKey="Filippatos G" first="Gerasimos" last="Filippatos">Gerasimos Filippatos</name><affiliation wicri:level="1"><nlm:affiliation>University of Cyprus Medical School, Shakolas Educational Center for Clinical Medicine, Nicosia, Cyprus.</nlm:affiliation><country xml:lang="fr">Chypre (pays)</country><wicri:regionArea>University of Cyprus Medical School, Shakolas Educational Center for Clinical Medicine, Nicosia</wicri:regionArea><wicri:noRegion>Nicosia</wicri:noRegion></affiliation></author><author><name sortKey="Lindenfeld, Joann" sort="Lindenfeld, Joann" uniqKey="Lindenfeld J" first="Joann" last="Lindenfeld">Joann Lindenfeld</name><affiliation wicri:level="2"><nlm:affiliation>Heart Failure and Transplantation Section, Vanderbilt Heart and Vascular Institute, Nashville, Tennessee.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Tennessee</region></placeName><wicri:cityArea>Heart Failure and Transplantation Section, Vanderbilt Heart and Vascular Institute, Nashville</wicri:cityArea></affiliation></author><author><name sortKey="Ahmad, Tariq" sort="Ahmad, Tariq" uniqKey="Ahmad T" first="Tariq" last="Ahmad">Tariq Ahmad</name><affiliation wicri:level="2"><nlm:affiliation>Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, Connecticut.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Connecticut</region></placeName><wicri:cityArea>Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven</wicri:cityArea></affiliation></author><author><name sortKey="Bhatt, Ankeet S" sort="Bhatt, Ankeet S" uniqKey="Bhatt A" first="Ankeet S" last="Bhatt">Ankeet S. Bhatt</name><affiliation wicri:level="2"><nlm:affiliation>Cardiovascular Division, Brigham and Women's Hospital, Boston, Massachusetts.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Cardiovascular Division, Brigham and Women's Hospital, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Carson, Peter E" sort="Carson, Peter E" uniqKey="Carson P" first="Peter E" last="Carson">Peter E. Carson</name><affiliation wicri:level="2"><nlm:affiliation>Department of Cardiology, Washington Veterans Affairs Medical Center, Washington, DC.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">District de Columbia</region></placeName><wicri:cityArea>Department of Cardiology, Washington Veterans Affairs Medical Center, Washington</wicri:cityArea></affiliation></author><author><name sortKey="Cleland, John G F" sort="Cleland, John G F" uniqKey="Cleland J" first="John G F" last="Cleland">John G F. Cleland</name><affiliation wicri:level="4"><nlm:affiliation>Robertson Institute of Biostatistics and Clinical Trials Unit, University of Glasgow, Glasgow, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Robertson Institute of Biostatistics and Clinical Trials Unit, University of Glasgow, Glasgow</wicri:regionArea><orgName type="university">Université de Glasgow</orgName><placeName><settlement type="city">Glasgow</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Felker, G Michael" sort="Felker, G Michael" uniqKey="Felker G" first="G Michael" last="Felker">G Michael Felker</name><affiliation wicri:level="2"><nlm:affiliation>Duke University Medical Center and Duke Clinical Research Institute, Durham, North Carolina.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Caroline du Nord</region></placeName><wicri:cityArea>Duke University Medical Center and Duke Clinical Research Institute, Durham</wicri:cityArea></affiliation></author><author><name sortKey="Januzzi, James L" sort="Januzzi, James L" uniqKey="Januzzi J" first="James L" last="Januzzi">James L. Januzzi</name><affiliation wicri:level="2"><nlm:affiliation>Cardiology Division, Massachusetts General Hospital and Baim Institute for Clinical Research, Boston, Massachusetts.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Cardiology Division, Massachusetts General Hospital and Baim Institute for Clinical Research, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Kitzman, Dalane W" sort="Kitzman, Dalane W" uniqKey="Kitzman D" first="Dalane W" last="Kitzman">Dalane W. Kitzman</name><affiliation wicri:level="2"><nlm:affiliation>Sections on Cardiovascular Medicine and Geriatrics, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Caroline du Nord</region></placeName><wicri:cityArea>Sections on Cardiovascular Medicine and Geriatrics, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem</wicri:cityArea></affiliation></author><author><name sortKey="Leifer, Eric S" sort="Leifer, Eric S" uniqKey="Leifer E" first="Eric S" last="Leifer">Eric S. Leifer</name><affiliation wicri:level="2"><nlm:affiliation>Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, Bethesda, Maryland.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, Bethesda</wicri:cityArea></affiliation></author><author><name sortKey="Lewis, Eldrin F" sort="Lewis, Eldrin F" uniqKey="Lewis E" first="Eldrin F" last="Lewis">Eldrin F. Lewis</name><affiliation wicri:level="2"><nlm:affiliation>Division of Cardiovascular Medicine, Stanford University, Palo Alto, California.</nlm:affiliation><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Division of Cardiovascular Medicine, Stanford University, Palo Alto</wicri:cityArea></affiliation></author><author><name sortKey="Mcmurray, John J V" sort="Mcmurray, John J V" uniqKey="Mcmurray J" first="John J V" last="Mcmurray">John J V. Mcmurray</name><affiliation wicri:level="4"><nlm:affiliation>BHF Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>BHF Cardiovascular Research Centre, University of Glasgow, Glasgow</wicri:regionArea><orgName type="university">Université de Glasgow</orgName><placeName><settlement type="city">Glasgow</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Mentz, Robert J" sort="Mentz, Robert J" uniqKey="Mentz R" first="Robert J" last="Mentz">Robert J. Mentz</name><affiliation wicri:level="2"><nlm:affiliation>Duke University Medical Center and Duke Clinical Research Institute, Durham, North Carolina.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Caroline du Nord</region></placeName><wicri:cityArea>Duke University Medical Center and Duke Clinical Research Institute, Durham</wicri:cityArea></affiliation></author><author><name sortKey="Solomon, Scott D" sort="Solomon, Scott D" uniqKey="Solomon S" first="Scott D" last="Solomon">Scott D. Solomon</name><affiliation wicri:level="2"><nlm:affiliation>Cardiovascular Division, Brigham and Women's Hospital, Boston, Massachusetts.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Cardiovascular Division, Brigham and Women's Hospital, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Stockbridge, Norman" sort="Stockbridge, Norman" uniqKey="Stockbridge N" first="Norman" last="Stockbridge">Norman Stockbridge</name><affiliation wicri:level="2"><nlm:affiliation>United States Food and Drug Administration, Silver Spring, Maryland.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>United States Food and Drug Administration, Silver Spring</wicri:cityArea></affiliation></author><author><name sortKey="Teerlink, John R" sort="Teerlink, John R" uniqKey="Teerlink J" first="John R" last="Teerlink">John R. Teerlink</name><affiliation wicri:level="2"><nlm:affiliation>Section of Cardiology, San Francisco Veterans Affairs Medical Center and School of Medicine, University of California-San Francisco, San Francisco, California. Electronic address: https://twitter.com/jteerlinkmd.</nlm:affiliation><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Section of Cardiology, San Francisco Veterans Affairs Medical Center and School of Medicine, University of California-San Francisco, San Francisco</wicri:cityArea></affiliation></author><author><name sortKey="Vaduganathan, Muthiah" sort="Vaduganathan, Muthiah" uniqKey="Vaduganathan M" first="Muthiah" last="Vaduganathan">Muthiah Vaduganathan</name><affiliation wicri:level="2"><nlm:affiliation>Cardiovascular Division, Brigham and Women's Hospital, Boston, Massachusetts.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Cardiovascular Division, Brigham and Women's Hospital, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Vardeny, Orly" sort="Vardeny, Orly" uniqKey="Vardeny O" first="Orly" last="Vardeny">Orly Vardeny</name><affiliation wicri:level="2"><nlm:affiliation>Pharmacy Practice Division, Minneapolis VA Center for Care Delivery and Outcomes Research and University of Minnesota, Minneapolis, Minnesota.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Minnesota</region></placeName><wicri:cityArea>Pharmacy Practice Division, Minneapolis VA Center for Care Delivery and Outcomes Research and University of Minnesota, Minneapolis</wicri:cityArea></affiliation></author><author><name sortKey="Whellan, David J" sort="Whellan, David J" uniqKey="Whellan D" first="David J" last="Whellan">David J. Whellan</name><affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName><wicri:cityArea>Department of Medicine, Thomas Jefferson University, Philadelphia</wicri:cityArea></affiliation></author><author><name sortKey="Wittes, Janet" sort="Wittes, Janet" uniqKey="Wittes J" first="Janet" last="Wittes">Janet Wittes</name><affiliation wicri:level="2"><nlm:affiliation>Statistics Collaborative, Washington, DC.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">District de Columbia</region></placeName><wicri:cityArea>Statistics Collaborative, Washington</wicri:cityArea></affiliation></author><author><name sortKey="Anker, Stefan D" sort="Anker, Stefan D" uniqKey="Anker S" first="Stefan D" last="Anker">Stefan D. Anker</name><affiliation wicri:level="3"><nlm:affiliation>Division of Cardiology and Metabolism, Department of Cardiology, Berlin-Brandenburg Center for Regenerative Therapies, German Centre for Cardiovascular Research Partner Site Berlin, Charité Universitätsmedizin Berlin, Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Cardiology and Metabolism, Department of Cardiology, Berlin-Brandenburg Center for Regenerative Therapies, German Centre for Cardiovascular Research Partner Site Berlin, Charité Universitätsmedizin Berlin, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="O Connor, Christopher M" sort="O Connor, Christopher M" uniqKey="O Connor C" first="Christopher M" last="O'Connor">Christopher M. O'Connor</name><affiliation wicri:level="2"><nlm:affiliation>Inova Heart and Vascular Institute, Falls Church, Virginia; Duke University Medical Center and Duke Clinical Research Institute, Durham, North Carolina. Electronic address: https://twitter.com/coconnormd.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Caroline du Nord</region></placeName><wicri:cityArea>Inova Heart and Vascular Institute, Falls Church, Virginia; Duke University Medical Center and Duke Clinical Research Institute, Durham</wicri:cityArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:33183511</idno><idno type="pmid">33183511</idno><idno type="doi">10.1016/j.jacc.2020.09.544</idno><idno type="wicri:Area/Main/Corpus">000042</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000042</idno><idno type="wicri:Area/Main/Curation">000042</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000042</idno><idno type="wicri:Area/Main/Exploration">000042</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Conduct of Clinical Trials in the Era of COVID-19: JACC Scientific Expert Panel.</title><author><name sortKey="Psotka, Mitchell A" sort="Psotka, Mitchell A" uniqKey="Psotka M" first="Mitchell A" last="Psotka">Mitchell A. Psotka</name><affiliation wicri:level="2"><nlm:affiliation>Inova Heart and Vascular Institute, Falls Church, Virginia. Electronic address: https://twitter.com/mpsotka.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Virginie</region></placeName><wicri:cityArea>Inova Heart and Vascular Institute, Falls Church</wicri:cityArea></affiliation></author><author><name sortKey="Abraham, William T" sort="Abraham, William T" uniqKey="Abraham W" first="William T" last="Abraham">William T. Abraham</name><affiliation wicri:level="2"><nlm:affiliation>Division of Cardiovascular Medicine, The Ohio State University, Columbus, Ohio. Electronic address: William.Abraham@osumc.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Ohio</region></placeName><wicri:cityArea>Division of Cardiovascular Medicine, The Ohio State University, Columbus</wicri:cityArea></affiliation></author><author><name sortKey="Fiuzat, Mona" sort="Fiuzat, Mona" uniqKey="Fiuzat M" first="Mona" last="Fiuzat">Mona Fiuzat</name><affiliation wicri:level="2"><nlm:affiliation>Duke University Medical Center and Duke Clinical Research Institute, Durham, North Carolina. Electronic address: https://twitter.com/mfiuzat.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Caroline du Nord</region></placeName><wicri:cityArea>Duke University Medical Center and Duke Clinical Research Institute, Durham</wicri:cityArea></affiliation></author><author><name sortKey="Filippatos, Gerasimos" sort="Filippatos, Gerasimos" uniqKey="Filippatos G" first="Gerasimos" last="Filippatos">Gerasimos Filippatos</name><affiliation wicri:level="1"><nlm:affiliation>University of Cyprus Medical School, Shakolas Educational Center for Clinical Medicine, Nicosia, Cyprus.</nlm:affiliation><country xml:lang="fr">Chypre (pays)</country><wicri:regionArea>University of Cyprus Medical School, Shakolas Educational Center for Clinical Medicine, Nicosia</wicri:regionArea><wicri:noRegion>Nicosia</wicri:noRegion></affiliation></author><author><name sortKey="Lindenfeld, Joann" sort="Lindenfeld, Joann" uniqKey="Lindenfeld J" first="Joann" last="Lindenfeld">Joann Lindenfeld</name><affiliation wicri:level="2"><nlm:affiliation>Heart Failure and Transplantation Section, Vanderbilt Heart and Vascular Institute, Nashville, Tennessee.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Tennessee</region></placeName><wicri:cityArea>Heart Failure and Transplantation Section, Vanderbilt Heart and Vascular Institute, Nashville</wicri:cityArea></affiliation></author><author><name sortKey="Ahmad, Tariq" sort="Ahmad, Tariq" uniqKey="Ahmad T" first="Tariq" last="Ahmad">Tariq Ahmad</name><affiliation wicri:level="2"><nlm:affiliation>Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, Connecticut.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Connecticut</region></placeName><wicri:cityArea>Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven</wicri:cityArea></affiliation></author><author><name sortKey="Bhatt, Ankeet S" sort="Bhatt, Ankeet S" uniqKey="Bhatt A" first="Ankeet S" last="Bhatt">Ankeet S. Bhatt</name><affiliation wicri:level="2"><nlm:affiliation>Cardiovascular Division, Brigham and Women's Hospital, Boston, Massachusetts.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Cardiovascular Division, Brigham and Women's Hospital, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Carson, Peter E" sort="Carson, Peter E" uniqKey="Carson P" first="Peter E" last="Carson">Peter E. Carson</name><affiliation wicri:level="2"><nlm:affiliation>Department of Cardiology, Washington Veterans Affairs Medical Center, Washington, DC.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">District de Columbia</region></placeName><wicri:cityArea>Department of Cardiology, Washington Veterans Affairs Medical Center, Washington</wicri:cityArea></affiliation></author><author><name sortKey="Cleland, John G F" sort="Cleland, John G F" uniqKey="Cleland J" first="John G F" last="Cleland">John G F. Cleland</name><affiliation wicri:level="4"><nlm:affiliation>Robertson Institute of Biostatistics and Clinical Trials Unit, University of Glasgow, Glasgow, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Robertson Institute of Biostatistics and Clinical Trials Unit, University of Glasgow, Glasgow</wicri:regionArea><orgName type="university">Université de Glasgow</orgName><placeName><settlement type="city">Glasgow</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Felker, G Michael" sort="Felker, G Michael" uniqKey="Felker G" first="G Michael" last="Felker">G Michael Felker</name><affiliation wicri:level="2"><nlm:affiliation>Duke University Medical Center and Duke Clinical Research Institute, Durham, North Carolina.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Caroline du Nord</region></placeName><wicri:cityArea>Duke University Medical Center and Duke Clinical Research Institute, Durham</wicri:cityArea></affiliation></author><author><name sortKey="Januzzi, James L" sort="Januzzi, James L" uniqKey="Januzzi J" first="James L" last="Januzzi">James L. Januzzi</name><affiliation wicri:level="2"><nlm:affiliation>Cardiology Division, Massachusetts General Hospital and Baim Institute for Clinical Research, Boston, Massachusetts.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Cardiology Division, Massachusetts General Hospital and Baim Institute for Clinical Research, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Kitzman, Dalane W" sort="Kitzman, Dalane W" uniqKey="Kitzman D" first="Dalane W" last="Kitzman">Dalane W. Kitzman</name><affiliation wicri:level="2"><nlm:affiliation>Sections on Cardiovascular Medicine and Geriatrics, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Caroline du Nord</region></placeName><wicri:cityArea>Sections on Cardiovascular Medicine and Geriatrics, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem</wicri:cityArea></affiliation></author><author><name sortKey="Leifer, Eric S" sort="Leifer, Eric S" uniqKey="Leifer E" first="Eric S" last="Leifer">Eric S. Leifer</name><affiliation wicri:level="2"><nlm:affiliation>Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, Bethesda, Maryland.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, Bethesda</wicri:cityArea></affiliation></author><author><name sortKey="Lewis, Eldrin F" sort="Lewis, Eldrin F" uniqKey="Lewis E" first="Eldrin F" last="Lewis">Eldrin F. Lewis</name><affiliation wicri:level="2"><nlm:affiliation>Division of Cardiovascular Medicine, Stanford University, Palo Alto, California.</nlm:affiliation><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Division of Cardiovascular Medicine, Stanford University, Palo Alto</wicri:cityArea></affiliation></author><author><name sortKey="Mcmurray, John J V" sort="Mcmurray, John J V" uniqKey="Mcmurray J" first="John J V" last="Mcmurray">John J V. Mcmurray</name><affiliation wicri:level="4"><nlm:affiliation>BHF Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>BHF Cardiovascular Research Centre, University of Glasgow, Glasgow</wicri:regionArea><orgName type="university">Université de Glasgow</orgName><placeName><settlement type="city">Glasgow</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Mentz, Robert J" sort="Mentz, Robert J" uniqKey="Mentz R" first="Robert J" last="Mentz">Robert J. Mentz</name><affiliation wicri:level="2"><nlm:affiliation>Duke University Medical Center and Duke Clinical Research Institute, Durham, North Carolina.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Caroline du Nord</region></placeName><wicri:cityArea>Duke University Medical Center and Duke Clinical Research Institute, Durham</wicri:cityArea></affiliation></author><author><name sortKey="Solomon, Scott D" sort="Solomon, Scott D" uniqKey="Solomon S" first="Scott D" last="Solomon">Scott D. Solomon</name><affiliation wicri:level="2"><nlm:affiliation>Cardiovascular Division, Brigham and Women's Hospital, Boston, Massachusetts.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Cardiovascular Division, Brigham and Women's Hospital, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Stockbridge, Norman" sort="Stockbridge, Norman" uniqKey="Stockbridge N" first="Norman" last="Stockbridge">Norman Stockbridge</name><affiliation wicri:level="2"><nlm:affiliation>United States Food and Drug Administration, Silver Spring, Maryland.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>United States Food and Drug Administration, Silver Spring</wicri:cityArea></affiliation></author><author><name sortKey="Teerlink, John R" sort="Teerlink, John R" uniqKey="Teerlink J" first="John R" last="Teerlink">John R. Teerlink</name><affiliation wicri:level="2"><nlm:affiliation>Section of Cardiology, San Francisco Veterans Affairs Medical Center and School of Medicine, University of California-San Francisco, San Francisco, California. Electronic address: https://twitter.com/jteerlinkmd.</nlm:affiliation><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Section of Cardiology, San Francisco Veterans Affairs Medical Center and School of Medicine, University of California-San Francisco, San Francisco</wicri:cityArea></affiliation></author><author><name sortKey="Vaduganathan, Muthiah" sort="Vaduganathan, Muthiah" uniqKey="Vaduganathan M" first="Muthiah" last="Vaduganathan">Muthiah Vaduganathan</name><affiliation wicri:level="2"><nlm:affiliation>Cardiovascular Division, Brigham and Women's Hospital, Boston, Massachusetts.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Cardiovascular Division, Brigham and Women's Hospital, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Vardeny, Orly" sort="Vardeny, Orly" uniqKey="Vardeny O" first="Orly" last="Vardeny">Orly Vardeny</name><affiliation wicri:level="2"><nlm:affiliation>Pharmacy Practice Division, Minneapolis VA Center for Care Delivery and Outcomes Research and University of Minnesota, Minneapolis, Minnesota.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Minnesota</region></placeName><wicri:cityArea>Pharmacy Practice Division, Minneapolis VA Center for Care Delivery and Outcomes Research and University of Minnesota, Minneapolis</wicri:cityArea></affiliation></author><author><name sortKey="Whellan, David J" sort="Whellan, David J" uniqKey="Whellan D" first="David J" last="Whellan">David J. Whellan</name><affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName><wicri:cityArea>Department of Medicine, Thomas Jefferson University, Philadelphia</wicri:cityArea></affiliation></author><author><name sortKey="Wittes, Janet" sort="Wittes, Janet" uniqKey="Wittes J" first="Janet" last="Wittes">Janet Wittes</name><affiliation wicri:level="2"><nlm:affiliation>Statistics Collaborative, Washington, DC.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">District de Columbia</region></placeName><wicri:cityArea>Statistics Collaborative, Washington</wicri:cityArea></affiliation></author><author><name sortKey="Anker, Stefan D" sort="Anker, Stefan D" uniqKey="Anker S" first="Stefan D" last="Anker">Stefan D. Anker</name><affiliation wicri:level="3"><nlm:affiliation>Division of Cardiology and Metabolism, Department of Cardiology, Berlin-Brandenburg Center for Regenerative Therapies, German Centre for Cardiovascular Research Partner Site Berlin, Charité Universitätsmedizin Berlin, Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Cardiology and Metabolism, Department of Cardiology, Berlin-Brandenburg Center for Regenerative Therapies, German Centre for Cardiovascular Research Partner Site Berlin, Charité Universitätsmedizin Berlin, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="O Connor, Christopher M" sort="O Connor, Christopher M" uniqKey="O Connor C" first="Christopher M" last="O'Connor">Christopher M. O'Connor</name><affiliation wicri:level="2"><nlm:affiliation>Inova Heart and Vascular Institute, Falls Church, Virginia; Duke University Medical Center and Duke Clinical Research Institute, Durham, North Carolina. Electronic address: https://twitter.com/coconnormd.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Caroline du Nord</region></placeName><wicri:cityArea>Inova Heart and Vascular Institute, Falls Church, Virginia; Duke University Medical Center and Duke Clinical Research Institute, Durham</wicri:cityArea></affiliation></author></analytic><series><title level="j">Journal of the American College of Cardiology</title><idno type="eISSN">1558-3597</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>COVID-19 (MeSH)</term><term>Clinical Trials as Topic (MeSH)</term><term>Coronavirus Infections (MeSH)</term><term>Endpoint Determination (MeSH)</term><term>Humans (MeSH)</term><term>Pandemics (MeSH)</term><term>Pneumonia, Viral (MeSH)</term><term>Socioeconomic Factors (MeSH)</term><term>Statistics as Topic (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Détermination du point final (MeSH)</term><term>Essais cliniques comme sujet (MeSH)</term><term>Facteurs socioéconomiques (MeSH)</term><term>Humains (MeSH)</term><term>Infections à coronavirus (MeSH)</term><term>Pandémies (MeSH)</term><term>Pneumopathie virale (MeSH)</term><term>Statistiques comme sujet (MeSH)</term></keywords><keywords scheme="MESH" xml:lang="en"><term>COVID-19</term><term>Clinical Trials as Topic</term><term>Coronavirus Infections</term><term>Endpoint Determination</term><term>Humans</term><term>Pandemics</term><term>Pneumonia, Viral</term><term>Socioeconomic Factors</term><term>Statistics as Topic</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Détermination du point final</term><term>Essais cliniques comme sujet</term><term>Facteurs socioéconomiques</term><term>Humains</term><term>Infections à coronavirus</term><term>Pandémies</term><term>Pneumopathie virale</term><term>Statistiques comme sujet</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The coronavirus disease-2019 (COVID-19) pandemic has profoundly changed clinical care and research, including the conduct of clinical trials, and the clinical research ecosystem will need to adapt to this transformed environment. The Heart Failure Academic Research Consortium is a partnership between the Heart Failure Collaboratory and the Academic Research Consortium, composed of academic investigators from the United States and Europe, patients, the U.S. Food and Drug Administration, the National Institutes of Health, and industry members. A series of meetings were convened to address the challenges caused by the COVID-19 pandemic, review options for maintaining or altering best practices, and establish key recommendations for the conduct and analysis of clinical trials for cardiovascular disease and heart failure. This paper summarizes the discussions and expert consensus recommendations.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">33183511</PMID><DateCompleted><Year>2020</Year><Month>11</Month><Day>19</Day></DateCompleted><DateRevised><Year>2020</Year><Month>12</Month><Day>10</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1558-3597</ISSN><JournalIssue CitedMedium="Internet"><Volume>76</Volume><Issue>20</Issue><PubDate><Year>2020</Year><Month>11</Month><Day>17</Day></PubDate></JournalIssue><Title>Journal of the American College of Cardiology</Title><ISOAbbreviation>J Am Coll Cardiol</ISOAbbreviation></Journal><ArticleTitle>Conduct of Clinical Trials in the Era of COVID-19: JACC Scientific Expert Panel.</ArticleTitle><Pagination><MedlinePgn>2368-2378</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S0735-1097(20)37234-X</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.jacc.2020.09.544</ELocationID><Abstract><AbstractText>The coronavirus disease-2019 (COVID-19) pandemic has profoundly changed clinical care and research, including the conduct of clinical trials, and the clinical research ecosystem will need to adapt to this transformed environment. The Heart Failure Academic Research Consortium is a partnership between the Heart Failure Collaboratory and the Academic Research Consortium, composed of academic investigators from the United States and Europe, patients, the U.S. Food and Drug Administration, the National Institutes of Health, and industry members. A series of meetings were convened to address the challenges caused by the COVID-19 pandemic, review options for maintaining or altering best practices, and establish key recommendations for the conduct and analysis of clinical trials for cardiovascular disease and heart failure. This paper summarizes the discussions and expert consensus recommendations.</AbstractText><CopyrightInformation>Copyright © 2020 The Authors. Published by Elsevier Inc. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Psotka</LastName><ForeName>Mitchell A</ForeName><Initials>MA</Initials><AffiliationInfo><Affiliation>Inova Heart and Vascular Institute, Falls Church, Virginia. Electronic address: https://twitter.com/mpsotka.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Abraham</LastName><ForeName>William T</ForeName><Initials>WT</Initials><AffiliationInfo><Affiliation>Division of Cardiovascular Medicine, The Ohio State University, Columbus, Ohio. Electronic address: William.Abraham@osumc.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fiuzat</LastName><ForeName>Mona</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Duke University Medical Center and Duke Clinical Research Institute, Durham, North Carolina. Electronic address: https://twitter.com/mfiuzat.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Filippatos</LastName><ForeName>Gerasimos</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>University of Cyprus Medical School, Shakolas Educational Center for Clinical Medicine, Nicosia, Cyprus.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lindenfeld</LastName><ForeName>JoAnn</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Heart Failure and Transplantation Section, Vanderbilt Heart and Vascular Institute, Nashville, Tennessee.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ahmad</LastName><ForeName>Tariq</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, Connecticut.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bhatt</LastName><ForeName>Ankeet S</ForeName><Initials>AS</Initials><AffiliationInfo><Affiliation>Cardiovascular Division, Brigham and Women's Hospital, Boston, Massachusetts.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Carson</LastName><ForeName>Peter E</ForeName><Initials>PE</Initials><AffiliationInfo><Affiliation>Department of Cardiology, Washington Veterans Affairs Medical Center, Washington, DC.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cleland</LastName><ForeName>John G F</ForeName><Initials>JGF</Initials><AffiliationInfo><Affiliation>Robertson Institute of Biostatistics and Clinical Trials Unit, University of Glasgow, Glasgow, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Felker</LastName><ForeName>G Michael</ForeName><Initials>GM</Initials><AffiliationInfo><Affiliation>Duke University Medical Center and Duke Clinical Research Institute, Durham, North Carolina.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Januzzi</LastName><ForeName>James L</ForeName><Initials>JL</Initials><Suffix>Jr</Suffix><AffiliationInfo><Affiliation>Cardiology Division, Massachusetts General Hospital and Baim Institute for Clinical Research, Boston, Massachusetts.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kitzman</LastName><ForeName>Dalane W</ForeName><Initials>DW</Initials><AffiliationInfo><Affiliation>Sections on Cardiovascular Medicine and Geriatrics, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Leifer</LastName><ForeName>Eric S</ForeName><Initials>ES</Initials><AffiliationInfo><Affiliation>Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, Bethesda, Maryland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lewis</LastName><ForeName>Eldrin F</ForeName><Initials>EF</Initials><AffiliationInfo><Affiliation>Division of Cardiovascular Medicine, Stanford University, Palo Alto, California.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>McMurray</LastName><ForeName>John J V</ForeName><Initials>JJV</Initials><AffiliationInfo><Affiliation>BHF Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mentz</LastName><ForeName>Robert J</ForeName><Initials>RJ</Initials><AffiliationInfo><Affiliation>Duke University Medical Center and Duke Clinical Research Institute, Durham, North Carolina.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Solomon</LastName><ForeName>Scott D</ForeName><Initials>SD</Initials><AffiliationInfo><Affiliation>Cardiovascular Division, Brigham and Women's Hospital, Boston, Massachusetts.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Stockbridge</LastName><ForeName>Norman</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>United States Food and Drug Administration, Silver Spring, Maryland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Teerlink</LastName><ForeName>John R</ForeName><Initials>JR</Initials><AffiliationInfo><Affiliation>Section of Cardiology, San Francisco Veterans Affairs Medical Center and School of Medicine, University of California-San Francisco, San Francisco, California. Electronic address: https://twitter.com/jteerlinkmd.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vaduganathan</LastName><ForeName>Muthiah</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Cardiovascular Division, Brigham and Women's Hospital, Boston, Massachusetts.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vardeny</LastName><ForeName>Orly</ForeName><Initials>O</Initials><AffiliationInfo><Affiliation>Pharmacy Practice Division, Minneapolis VA Center for Care Delivery and Outcomes Research and University of Minnesota, Minneapolis, Minnesota.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Whellan</LastName><ForeName>David J</ForeName><Initials>DJ</Initials><AffiliationInfo><Affiliation>Department of Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wittes</LastName><ForeName>Janet</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Statistics Collaborative, Washington, DC.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Anker</LastName><ForeName>Stefan D</ForeName><Initials>SD</Initials><AffiliationInfo><Affiliation>Division of Cardiology and Metabolism, Department of Cardiology, Berlin-Brandenburg Center for Regenerative Therapies, German Centre for Cardiovascular Research Partner Site Berlin, Charité Universitätsmedizin Berlin, Berlin, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>O'Connor</LastName><ForeName>Christopher M</ForeName><Initials>CM</Initials><AffiliationInfo><Affiliation>Inova Heart and Vascular Institute, Falls Church, Virginia; Duke University Medical Center and Duke Clinical Research Institute, Durham, North Carolina. Electronic address: https://twitter.com/coconnormd.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016446">Consensus Development Conference</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016454">Review</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>J Am Coll Cardiol</MedlineTA><NlmUniqueID>8301365</NlmUniqueID><ISSNLinking>0735-1097</ISSNLinking></MedlineJournalInfo><SupplMeshList><SupplMeshName Type="Disease" UI="C000657245">COVID-19</SupplMeshName></SupplMeshList><CitationSubset>AIM</CitationSubset><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000086382" MajorTopicYN="N">COVID-19</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002986" MajorTopicYN="Y">Clinical Trials as Topic</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018352" MajorTopicYN="Y">Coronavirus Infections</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D023381" MajorTopicYN="N">Endpoint Determination</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D058873" MajorTopicYN="Y">Pandemics</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011024" MajorTopicYN="Y">Pneumonia, Viral</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012959" MajorTopicYN="N">Socioeconomic Factors</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013223" MajorTopicYN="N">Statistics as Topic</DescriptorName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="Y">COVID-19</Keyword><Keyword MajorTopicYN="Y">clinical trial</Keyword><Keyword MajorTopicYN="Y">endpoint ascertainment</Keyword><Keyword MajorTopicYN="Y">heart failure</Keyword></KeywordList><CoiStatement>Author Relationship With Industry Dr. Psotka has received consulting fees from Amgen, Cytokinetics, and Windtree; and has received grant support from the U.S. Food and Drug Administration. Dr. Abraham has received consulting fees from Abbott, Boehringer Ingelheim, CVRx, Edwards Lifesciences, and Respicardia; has received salary support from V-Wave; and has received research support from the U.S. National Institutes of Health/National Heart, Lung, and Blood Institute. Dr. Filippatos has received consulting income from Boehringer Ingelheim, Medtronic, Novartis, Servier, and Vifor; and has received lecture fees from Merck. Dr. Lindenfeld has received consulting fees from Novartis, Abbott, ResMed, V-Wave, CVRx, and Cytokinetics. Dr. Ahmad has received consulting fees from Amgen, Cytokinetics, Relypsa, and Novartis. Dr. Bhatt has received consulting fees from Sanofi Pasteur; and participates in clinical endpoint committees for the U.S. National Institutes of Health. Dr. Cleland has received consulting fees from Abbott, Amgen, Bayer, Medtronic, Novartis, Pharmacosmos, Vifor, Bristol Myers Squibb, and Servier; and has received research grants from Amgen, Bayer, Novartis, Pharmacosmos, Vifor, Bristol Myers Squibb, and Servier. Dr. Felker has received research grants from the National Heart, Lung, and Blood Institute, American Heart Association, Amgen, Merck, Cytokinetics, and Roche Diagnostics; and has received consulting fees from Novartis, Amgen, Bristol Myers Squibb, Cytokinetics, Medtronic, Cardionomic, Relypsa, V-Wave, Myokardia, Innolife, EBR Systems, Arena, Abbott, Sphingotec, Roche Diagnostics, Alnylam, LivaNova, Windtree Therapeutics, Rocket Pharma, and scPharmaceuticals. Dr. Januzzi is a trustee of the American College of Cardiology; has received grant support from Applied Therapeutics, Novartis Pharmaceuticals, and Abbott Diagnostics; has received consulting income from Abbott, Janssen, Novartis, Pfizer, Merck, and Roche Diagnostics; and participates in clinical endpoint committees/data safety monitoring boards for Abbott, AbbVie, Amgen, Boehringer Ingelheim, Janssen, and Takeda. Dr. Kitzman has received consulting fees from AstraZeneca, Bayer, Novartis, Merck, Pfizer, Boehringer Ingelheim, AbbVie, DCRI, and Corvia; has received grant support from AstraZeneca, Bayer, and Novartis; and has stock in Gilead. Dr. Lewis has received consulting fees from Novartis; and has received institutional research grant support from Amgen, Novartis, and Sanofi. Dr. McMurray has received financial support from Bayer, Cardiorentis, Amgen, Oxford University, Theracos, Abbvie, DalCor, Pfizer, Merck, Novartis, GlaxoSmithKline, Bristol Myers Squibb, Vifor-Fresenius, Kidney Research UK, and AstraZeneca. Dr. Mentz has received consulting fees from Abbott, Amgen, AstraZeneca, Bayer, Boston Scientific, Janssen, Luitpold, Medtronic, Merck, Novartis, and Sanofi; and has received research grants from Akros, Amgen, AstraZeneca, Bayer, Bristol Myers Squibb, GlaxoSmithKline, Gilead, InnoLife, Luitpold/American Reagent, Novartis, Otsuka, ResMed, and the U.S. National Institutes of Health grants U01HL125511-01A1 and R01AG045551-01A1. Dr. Solomon has received research grants from Alnylam, Amgen, AstraZeneca, Bellerophon, Bristol Myers Squibb, Celladon, Cytokinetics, Eidos, Gilead, GlaxoSmithKline, Ionis, Lone Star Heart, Mesoblast, MyoKardia, U.S. National Institutes of Health/National Heart, Lung, and Blood Institute, Novartis, Sanofi Pasteur, and Theracos; and has received consulting fees from Akros, Alnylam, Amgen, AstraZeneca, Bayer, Bristol Myers Squibb, Cardior, Corvia, Cytokinetics, Gilead, GlaxoSmithKline, Ironwood, Merck Sharp & Dohme, Novartis, Roche, Takeda, Theracos, Quantum Genetics, Cardurion, AoBiome, Janssen, and Cardiac Dimensions. Dr. Teerlink has received consulting fees from Amgen, Bayer, Cytokinetics, Novartis, and Stealth Health; and has received research funding from Abbott, Amgen, Bayer, Bristol Myers Squibb, Novartis, and scPharmaceuticals. Dr. Vaduganathan is supported by the KL2/Catalyst Medical Research Investigator Training award from Harvard Catalyst (NIH/NCATS Award UL 1TR002541); and has served on Advisory Boards for Amgen, AstraZeneca, Baxter Healthcare, Bayer AG, Boehringer Ingelheim, Cytokinetics, and Relypsa. Dr. Vardeny has received consulting fees from Novartis; and has received research grants from AstraZeneca and Sanofi Pasteur. Dr. Whellan has received grant support from the U.S. National Institutes of Health (R01AG045551). Dr. Wittes reports that the company for which she works, Statistics Collaborative, has contracts with many companies, some of which are developing treatments for heart failure. Dr. Anker has received clinical trial–related fees from Abbott Vascular, Servier, Vifor, Bayer, Boehringer Ingelheim, Thermo Fisher, Respicardia, and Novartis. Dr. O’Connor has received research support from Roche Diagnostics and Merck; has been a consultant for Bristol Myers Squibb, Merck, Windtree, and Neurotronik; and is a co-owner of Biscardia. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.</CoiStatement></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>06</Month><Day>22</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2020</Year><Month>08</Month><Day>12</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2020</Year><Month>09</Month><Day>09</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>11</Month><Day>13</Day><Hour>5</Hour><Minute>34</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>11</Month><Day>14</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>11</Month><Day>20</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">33183511</ArticleId><ArticleId IdType="pii">S0735-1097(20)37234-X</ArticleId><ArticleId IdType="doi">10.1016/j.jacc.2020.09.544</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Allemagne</li><li>Chypre (pays)</li><li>Royaume-Uni</li><li>États-Unis</li></country><region><li>Berlin</li><li>Californie</li><li>Caroline du Nord</li><li>Connecticut</li><li>District de Columbia</li><li>Maryland</li><li>Massachusetts</li><li>Minnesota</li><li>Ohio</li><li>Pennsylvanie</li><li>Tennessee</li><li>Virginie</li><li>Écosse</li></region><settlement><li>Berlin</li><li>Glasgow</li></settlement><orgName><li>Université de Glasgow</li></orgName></list><tree><country name="États-Unis"><region name="Virginie"><name sortKey="Psotka, Mitchell A" sort="Psotka, Mitchell A" uniqKey="Psotka M" first="Mitchell A" last="Psotka">Mitchell A. Psotka</name></region><name sortKey="Abraham, William T" sort="Abraham, William T" uniqKey="Abraham W" first="William T" last="Abraham">William T. Abraham</name><name sortKey="Ahmad, Tariq" sort="Ahmad, Tariq" uniqKey="Ahmad T" first="Tariq" last="Ahmad">Tariq Ahmad</name><name sortKey="Bhatt, Ankeet S" sort="Bhatt, Ankeet S" uniqKey="Bhatt A" first="Ankeet S" last="Bhatt">Ankeet S. Bhatt</name><name sortKey="Carson, Peter E" sort="Carson, Peter E" uniqKey="Carson P" first="Peter E" last="Carson">Peter E. Carson</name><name sortKey="Felker, G Michael" sort="Felker, G Michael" uniqKey="Felker G" first="G Michael" last="Felker">G Michael Felker</name><name sortKey="Fiuzat, Mona" sort="Fiuzat, Mona" uniqKey="Fiuzat M" first="Mona" last="Fiuzat">Mona Fiuzat</name><name sortKey="Januzzi, James L" sort="Januzzi, James L" uniqKey="Januzzi J" first="James L" last="Januzzi">James L. Januzzi</name><name sortKey="Kitzman, Dalane W" sort="Kitzman, Dalane W" uniqKey="Kitzman D" first="Dalane W" last="Kitzman">Dalane W. Kitzman</name><name sortKey="Leifer, Eric S" sort="Leifer, Eric S" uniqKey="Leifer E" first="Eric S" last="Leifer">Eric S. Leifer</name><name sortKey="Lewis, Eldrin F" sort="Lewis, Eldrin F" uniqKey="Lewis E" first="Eldrin F" last="Lewis">Eldrin F. Lewis</name><name sortKey="Lindenfeld, Joann" sort="Lindenfeld, Joann" uniqKey="Lindenfeld J" first="Joann" last="Lindenfeld">Joann Lindenfeld</name><name sortKey="Mentz, Robert J" sort="Mentz, Robert J" uniqKey="Mentz R" first="Robert J" last="Mentz">Robert J. Mentz</name><name sortKey="O Connor, Christopher M" sort="O Connor, Christopher M" uniqKey="O Connor C" first="Christopher M" last="O'Connor">Christopher M. O'Connor</name><name sortKey="Solomon, Scott D" sort="Solomon, Scott D" uniqKey="Solomon S" first="Scott D" last="Solomon">Scott D. Solomon</name><name sortKey="Stockbridge, Norman" sort="Stockbridge, Norman" uniqKey="Stockbridge N" first="Norman" last="Stockbridge">Norman Stockbridge</name><name sortKey="Teerlink, John R" sort="Teerlink, John R" uniqKey="Teerlink J" first="John R" last="Teerlink">John R. Teerlink</name><name sortKey="Vaduganathan, Muthiah" sort="Vaduganathan, Muthiah" uniqKey="Vaduganathan M" first="Muthiah" last="Vaduganathan">Muthiah Vaduganathan</name><name sortKey="Vardeny, Orly" sort="Vardeny, Orly" uniqKey="Vardeny O" first="Orly" last="Vardeny">Orly Vardeny</name><name sortKey="Whellan, David J" sort="Whellan, David J" uniqKey="Whellan D" first="David J" last="Whellan">David J. Whellan</name><name sortKey="Wittes, Janet" sort="Wittes, Janet" uniqKey="Wittes J" first="Janet" last="Wittes">Janet Wittes</name></country><country name="Chypre (pays)"><noRegion><name sortKey="Filippatos, Gerasimos" sort="Filippatos, Gerasimos" uniqKey="Filippatos G" first="Gerasimos" last="Filippatos">Gerasimos Filippatos</name></noRegion></country><country name="Royaume-Uni"><region name="Écosse"><name sortKey="Cleland, John G F" sort="Cleland, John G F" uniqKey="Cleland J" first="John G F" last="Cleland">John G F. Cleland</name></region><name sortKey="Mcmurray, John J V" sort="Mcmurray, John J V" uniqKey="Mcmurray J" first="John J V" last="Mcmurray">John J V. Mcmurray</name></country><country name="Allemagne"><region name="Berlin"><name sortKey="Anker, Stefan D" sort="Anker, Stefan D" uniqKey="Anker S" first="Stefan D" last="Anker">Stefan D. Anker</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Wicri/explor/CovidPublicV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000191 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000191 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Wicri
|area= CovidPublicV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:33183511
|texte= Conduct of Clinical Trials in the Era of COVID-19: JACC Scientific Expert Panel.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:33183511" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a CovidPublicV1
| This area was generated with Dilib version V0.6.38. |  |